Green nanotechnology combines the principles of green chemistry and nanotechnology to bring about nanomaterials for various applications. By using eco-friendly and non-toxic approaches, the synthesize of nanomaterials has circumvented the effects of hazardous chemicals, unwieldy process and innocuous handling adhering to the sustainable developmental goals. Various sources such as plants, microbes, and animals are being used to synthesize nanoparticles, reducing the overall cost of production. Such nanoparticles have shown to report antimicrobial, anticancer, anti-diabetic, antioxidant and anti-inflammatory properties.
Nature has provided various biological materials that are used in traditional medicine for treating innumerable ailments, for over many eras and even now they have gained global reputation. However, they tend to have some limitations when used on their native form in aspects like solubility and stability. These therapeutics when integrated with nanotechnologies can circumvent the issues of potency and efficacy. The integral medicines as nano formulations, has an improved mechanical and biochemical properties with an overall evolution in therapeutics.
Personalized medicine aims to tailor disease prevention, treatment and diagnosis for specific patients based on their genetic, molecular and phenotypic profiles. The integration of nanotechnology enhances the personalized medicine by enabling precise, targeted drug delivery, specific therapeutic for individual patients. Nanocarriers like nanoparticles, lipid-based nanoparticle, antibody tagged nanoparticles and liposomes profess unique property like controlled drug release, targeted drug delivery and limits non-specific binding. This approach plays a crucial role in genomics-therapy, cancer diagnosis and pharmacogenomics. This review highlights the importance of personalized medicine in nanotechnology, nanomaterial-based therapeutics as a healthcare solution
Cancer is one of the leading causes of mortality worldwide, which is caused by abnormal growth of cells. Prevalence of morbidity is primarily due to late diagnosis and conventional therapeutic approach is time consuming and not effective to all cancer cells. Nanotechnology has emerged as a transformative platform in cancer treatments due to the precise and targeted drug delivery in a particular cell and damaging the cancer cells. Nanomaterials such as metallic nanoparticle, carbon-based nanoparticle, polymeric nanoparticle have the unique property that enhanced imaging sensitivity and controlled drug release. This review highlights the nanomaterials and clinical application in cancer diagnosis and therapy.